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Pokemon Polyclonal Antibody

Pokemon Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Pokemon Antibody (BS-0891R) in IHC (P)

Formalin-fixed and paraffin embedded human gastric carcinoma with Anti-Pokemon Polyclonal Antibody, Unconjugated (bs-0891R) at 1:200, followed by conjugation to the secondary antibody and DAB staining.

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产品信息

BS-0891R

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500

免疫组化（石蜡） (IHC (P))

1:200

免疫组化（冰冻） (IHC (F))

1:100-1:500

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1:500-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human Pokemon, amino acids 151-250.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals. Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DKFZp547O146; Factor binding IST protein 1; Factor that binds to inducer of short transcripts protein 1; FBI-1; HIV-1 1st-binding protein 1; HIV-1 inducer of short transcripts binding protein; leukemia/lymphoma related factor; Leukemia/lymphoma-related factor; lymphoma related factor; MGC99631; Osteoclast-derived zinc finger protein; POK erythroid myeloid ontogenic factor; POZ and Krueppel erythroid myeloid ontogenic factor; TIP21; TTF-I-interacting peptide 21; zi; zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein; Zinc finger and BTB domain-containing protein 7A; Zinc finger protein 857A

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基因别名: 9030619K07Rik; 9130006G12Rik; AI452336; FBI-1; FBI1; LRF; OCZF; Pokemon; TIP21; ZBTB7; ZBTB7A; ZNF857A

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UniProt ID: (Human) O95365, (Mouse) O88939, (Rat) Q9QZ48

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Entrez Gene ID: (Human) 51341, (Mouse) 16969, (Rat) 117107

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding protein binding histone acetyltransferase binding metal ion binding nucleic acid binding transcription factor activity, sequence-specific DNA binding C2H2 zinc finger transcription factor

参与通路

negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated multicellular organism development cell differentiation regulation of osteoclast differentiation negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter cartilage development