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产品信息
A304-005A-T
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 50 and 100
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exodeoxyribonuclease; CDC2 homolog; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125; POL D; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit; Polymerase D
基因别名: 125kDa; CDC2; CRCS10; MDPL; POLD; POLD1
UniProt ID: (Human) P28340, (Mouse) P52431
Entrez Gene ID: (Human) 5424, (Mouse) 18971
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5'-exodeoxyribonuclease activity
enzyme binding
metal ion binding
4 iron, 4 sulfur cluster binding
nucleic acid binding
nuclease activity
exonuclease activity
3'-5' exonuclease activity
transferase activity
nucleotidyltransferase activity
hydrolase activity
iron-sulfur cluster binding
DNA metabolism protein
telomere maintenance via recombination
telomere maintenance
DNA synthesis involved in DNA repair
DNA replication
DNA strand elongation involved in DNA replication
DNA repair
transcription-coupled nucleotide-excision repair
base-excision repair, gap-filling
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
response to UV
translesion synthesis
nucleotide-excision repair, DNA incision
cellular response to UV
DNA damage response, detection of DNA damage
DNA replication proofreading
fatty acid homeostasis
DNA-dependent DNA replication
DNA biosynthetic process
nucleic acid phosphodiester bond hydrolysis
