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产品信息
MA1-83403
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
1188/344
抗原
Progesterone conjugated to BSA
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_935162
产品详细信息
Mouse anti progesterone monoclonal antibody, clone 1188/344 is specific for progesterone, a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland.
靶标信息
Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation, pregnancy maintenance, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. Therapeutic progesterone is a synthetic form of the endogenous hormone progesterone. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. [National Center for Biotechnology Information. PubChem Compound Database; CID=5994]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 11-alpha-hydroxyprogesterone; Agolutin; C21H30O2; Crinone; Luteohormone; OHP; Pregn-4-ene-3; Progesterone-11a-hemisuccinate
