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QSOX1 Antibody (PA5-106300) in ICC/IF
Immunofluorescent analysis of QSOX1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and QSOX1 polyclonal antibody (Product # PA5-106300) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106300
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human QSOX1(Accession O00391), corresponding to amino acid residues L375-H425.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853977
产品详细信息
Antibody detects endogenous levels of total Quiescin Q6.
靶标信息
The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FAD-dependent sulfhydryl oxidase-2; hQSOX; mSOx; Quiescin Q6; quiescin Q6 sulfhydryl oxidase 1; RP11-502H18.3; rQSOX; Skin sulfhydryl oxidase; SOx-2; Sulfhydryl oxidase 1; testis tissue sperm-binding protein Li 62n; thiol oxidase 1
基因别名: 1300003H02Rik; Q6; QSCN6; QSOX; QSOX1; rSOx; SOx; Sox-2; Sox2; UNQ2520/PRO6013
UniProt ID: (Human) O00391, (Mouse) Q8BND5, (Rat) Q6IUU3
Entrez Gene ID: (Human) 5768, (Mouse) 104009, (Rat) 84491
