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Immunogen sequence: SFLGGLRSK NDVLSRSNVC INGNHVYLEQ PEAKGEIKDS SPSSSPSPKG FRKKHLFSST ENLAAGSWKE PAEGGGLSSD RQLSESSTKD SLKSMTLPSY RPAPLVSGDL RENMAPANSE ATKEAKESKK PESRRSSLLS LMTGKKDVAK GSEGENPLTV PGREKEGMLM GVKPGEDASG PAEDLVRRSE KDTAAVVSRQ GSSLNLFEDV QITEPEAEPE SKSEPRPPIS SPRAPQTRAV KPRLHPVKPM NAMATKVANC SLGTATIISE NLNNEVMMKK YSPSDPAFAY AQLTHDELIQ LVLKQKETIS KKEFQVRELE DYIDNLLVRV MEETPNILRI PTQVGKKAGK M (300-650 aa encoded by BC077720)
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein. Rab11-FIP1, by interacting with Rab GTPases, is involved in the endosomal recycling process and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis. Localized to the recycling endosome, the cytoplasmic membrane and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing. As the most highly expressed isoform, isoform two of Rab11-FIP1 is expressed in brain, lung, testis, small intestine, spleen and heart. Isoform two of Rab11-FIP1 also has been found to form a homooligomer and is believed to interact with many Rab GTPases, including Rab 4A, Rab 11A, Rab 11B and Rab 25.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CBBM; hCG_41347; Rab coupling protein; Rab effector protein; Rab-coupling protein; Rab-interacting recycling protein; RAB11 coupling protein; RAB11 family interacting protein 1 (class I); Rab11 family-interacting protein 1; Rab11-FIP1; rab11fip1 {ECO:0000250|UniProtKB:Q6WKZ4}
基因别名: 2010200K21Rik; 4833414G05Rik; NOEL1A; Rab11-FIP1; RAB11FIP1; RCP; RGD1562965
UniProt ID: (Human) Q6WKZ4, (Mouse) Q9D620, (Rat) Q3B7T9
Entrez Gene ID: (Human) 80223, (Mouse) 75767, (Rat) 498650