Proteintech

RAB27A Monoclonal Antibody (1C4B8)

RAB27A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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RAB27A Antibody (66058-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human lymphoma tissue slide using 66058-1-IG (RAB27A antibody) at dilution of 1:10000 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

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产品信息

66058-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:5,000-1:50,000

免疫组化（石蜡） (IHC (P))

1:5,000-1:20,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

1C4B8

抗原

RAB27A Fusion Protein Ag12382 (1-221 aa encoded by BC107680)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.41 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MSDGDYDYL IKFLALGDSG VGKTSVLYQY TDGKFNSKFI TTVGIDFREK RVVYRASGPD GATGRGQRIH LQLWDTAGQE RFRSLTTAFF RDAMGFLLLF DLTNEQSFLN VRNWISQLQM HAYCENPDIV LCGNKSDLED QRVVKEEEAI ALAEKYGIPY FETSAANGTN ISQAIEMLLD LIMKRMERCV DKSWIPEGVV RSNGHASTDQ LSEEKEKGAC GC (1-221 aa encoded by BC107680)

靶标信息

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.

仅用于科研。不用于诊断过程。未经明确授权不得转售。