Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
12471-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RAB40B Fusion Protein Ag3155 (1-278 aa encoded by BC018039)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSALGSPVR AYDFLLKFLL VGDSDVGKGE ILASLQDGAA ESTYGHPAGI DYKTTTILLD GRRVKLQLWD TSGQGRFCTI FRSYSRGAQG VILVYDIANR WSFDGIDRWI KEIDEHAPGV PKILVGNRLH LAFKRQVPTE QAQAYAERLG VTFFEVSPLC NFNITESFTE LARIVLLRHG MDRLWRPSKV LSLQDLCCRA VVSCTPVHLV DKLPLPIALR SHLKSFSMAN GLNARMMHGG SYSLTTSSTH KRSSLRKVKL VRPPQSPPKN CTRNSCKIS (1-278 aa encoded by BC018039 )
靶标信息
Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GTP-binding protein homologous to Saccharomyces cerevisiae SEC4; Protein Rar; Ras-related protein Rab-40B; sec4; SOCS box-containing protein RAR
基因别名: RAB40B; RAR; SEC4L
UniProt ID: (Human) Q12829
Entrez Gene ID: (Human) 10966
