Invitrogen

RAB5 Recombinant Rabbit Monoclonal Antibody (ST47-04)

RAB5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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RAB5 Antibody (MA5-32150) in IHC (P)

Immunohistochemical analysis of RAB5 of paraffin-embedded Mouse prostate tissue using a RAB5 Monoclonal antibody (Product #MA5-32150). Counter stained with hematoxylin.

RAB5 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

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产品信息

MA5-32150

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

ST47-04

抗原

Synthetic peptide within Human Rab5 aa 166-215

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2809440

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia.

Cell adhesion & migration

Desale SE,Chinnathambi S

MA5-32150 was used in Western Blot, Immunocytochemistry to suggest that microglia could be influenced to reduce extracellular Tau seed with dietary fatty acids.

Wed Dec 01 00:00:00 EST 2021

α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia.

Cell adhesion & migration

Desale SE,Chinnathambi S

MA5-32150 was used in Western Blot, Immunocytochemistry to suggest that microglia could be influenced to reduce extracellular Tau seed with dietary fatty acids.

Wed Dec 01 00:00:00 EST 2021

α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia.

Cell adhesion & migration

Desale SE,Chinnathambi S

MA5-32150 was used in Western Blot, Immunocytochemistry to suggest that microglia could be influenced to reduce extracellular Tau seed with dietary fatty acids.

Wed Dec 01 00:00:00 EST 2021

α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia.

Cell adhesion & migration

Desale SE,Chinnathambi S

MA5-32150 was used in Western Blot, Immunocytochemistry to suggest that microglia could be influenced to reduce extracellular Tau seed with dietary fatty acids.