Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 4
RACGAP1 Antibody (CF811639) in IHC (P)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human spleen tissue within the normal limits using anti-RACGAP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA811639)(1:2000).
产品信息
CF811639
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI3A5
抗原
Human recombinant protein fragment corresponding to amino acids 123-238 of human RACGAP1 produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: AKT; CYK4; ID; Male germ cell RacGap; MGC99656; MgcRacGAP; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase-activating protein 1; RAC-ALPHA; racgap1
基因别名: AI227039; AI327394; Band25; CYK4; gtl11; GTPase; HsCYK-4; ID-GAP; KIAA1478; MGCRACGAP; mKIAA1478; RACGAP1
UniProt ID: (Human) Q9H0H5, (Mouse) Q9WVM1
Entrez Gene ID: (Human) 29127, (Mouse) 26934, (Rat) 315298
mitotic cytokinesis
actomyosin contractile ring assembly
retrograde vesicle-mediated transport, Golgi to ER
microtubule-based movement
spermatogenesis
neuroblast proliferation
sulfate transport
embryo development
antigen processing and presentation of exogenous peptide antigen via MHC class II
positive regulation of cytokinesis
intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
mitotic spindle midzone assembly
regulation of attachment of spindle microtubules to kinetochore
transport
ion transport
cell cycle
signal transduction
multicellular organism development
cell differentiation
cell division
mitotic spindle assembly
