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产品信息
TA811221
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI2A12
抗原
Human recombinant protein fragment corresponding to amino acids 193-458 of human RAD21 produced in E.coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Double-strand-break repair protein rad21 homolog; FLJ25655; FLJ40596; h NXP-1; hHR21; KIAA0078RAD21; kleisin; Nuclear matrix protein 1; NXP-1; protein involved in DNA double-strand break repair; RAD21 homolog; SCC1 homolog; sister chromatid cohesion 1
基因别名: CDLS4; hHR21; HR21; HRAD21; KIAA0078; MCD1; NXP1; RAD21; SCC1
UniProt ID: (Human) O60216
Entrez Gene ID: (Human) 5885
double-strand break repair
DNA recombination
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
sister chromatid cohesion
mitotic nuclear division
reciprocal meiotic recombination
protein sumoylation
positive regulation of transcription from RNA polymerase II promoter
cell division
protein localization to chromatin
