Search Thermo Fisher Scientific
图: 1 / 1
This antibody detects mouse Rae-1 gamma as well as mouse Rae-1 alpha, 1 beta, 1 gamma and 1 epsilon in direct ELISAs and Western blots.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; mRNA export protein; MRNP41; RAE-1-gamma; Retinoic acid early-inducible protein 1-gamma; RP4-800J21.2
基因别名: RAE-1gamma; Raet1c
UniProt ID: (Mouse) O08604
Entrez Gene ID: (Mouse) 19370