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产品信息
PA5-115824
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RAPSN(Accession Q13702), corresponding to amino acid residues E372-V412.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900458
产品详细信息
Antibody detects endogenous levels of total Rapsyn.
靶标信息
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 43 kDa postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa acetylcholine receptor-associated protein; Acetylcholine receptor-associated 43 kDa protein; CMS1D; CMS1E; MGC3597; RAPsyn; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; RING finger protein 205
基因别名: 43kDa; CMS11; CMS4C; FADS; Nraps; Raps; RAPSN; RAPSYN; RNF205
UniProt ID: (Human) Q13702, (Mouse) P12672
Entrez Gene ID: (Human) 5913, (Rat) 362161, (Mouse) 19400
