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RAPSN Antibody (PA5-93169) in IHC (P)
Immunohistochemistry analysis of RAPSN in paraffin-embedded human stomach. Samples were incubated with RAPSN Polyclonal antibody (Product # PA5-93169) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-93169
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human RAPSN (NP_1160342)
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806652
产品详细信息
Immunogen sequence: MGQDQTKQQI EKGLQLYQSN QTEKALQVWT KVLEKSSDLM GRFRVLGCLV TAHSEMGRYK EMLKFAVVQI DTARELEDAD FLLESYLNLA RSNEKLCEFH KTISYCKTCL GLPGTRAGAQ LGGQVSLSMG NAFLGLSVFQ KALESFEKAL RYAHNNDDAM LECRVCCSLG SFYAQVKDYE KALFFPCKAA ELVNNYGKGW SLKYRAMSQY HMAVAYRLLG RLGSAMECCE ESMKIALQHG DRPLQALCLL CFADIHRSRG DLELSQLKLH CLSESIYRSK GLQRELRAHV VRFHECVEET ELYCGLCGES IGEKNSRLQA LPCSHIFHLR CLQNNGTRSC PNCRRSSMKP GFV; Positive Samples: B-cell, Mouse skeletal muscle, Mouse brain, Rat skeletal muscle, Rat brain; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, postsynaptic cell membrane, synapse
靶标信息
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 43 kDa postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa acetylcholine receptor-associated protein; Acetylcholine receptor-associated 43 kDa protein; CMS1D; CMS1E; MGC3597; RAPsyn; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; RING finger protein 205
基因别名: 43kDa; CMS11; CMS4C; FADS; Nraps; Raps; RAPSN; RAPSYN; RNF205
UniProt ID: (Human) Q13702, (Mouse) P12672
Entrez Gene ID: (Human) 5913, (Rat) 362161, (Mouse) 19400
