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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: PDDYSNFVIE DSVTTFKTIQ QIKSIIEKLD EPHEKYRKKR SSSAKYGSKE NPIVGKAS
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CM-AVM; CMAVM; DKFZp434N071; GAP1m; GTPase-activating protein 1m; GTPase-activating protein of RAS; p120RASGAP; PKWS; Ras GTPase-activating protein 2; RASA
基因别名: GAP1M; RASA2; RASGAP
UniProt ID: (Human) Q15283
Entrez Gene ID: (Human) 5922