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Immunogen sequence: SLQNASHHLE PNMDLINLLT LSLDLYHTED DIYKLSLVLE PRNSKSQPTS PTTPNKPVVP LEWALGVMPK PDPTVINKHI RKLVESVFRN YDHDHDGYIS QEDFESIAAN FPFLDSFCVL DKDQDGLISK DEMMAYFLRA KSQLHCKMGP GFIHNFQEMT YLKPTFCEHC AGFLWGIIKQ GYKCKDCGAN CHKQCKDLLV LACRRFARAP SLSSGHGSLP GSPSLPPAQD EVFEFPGVTA GHRDLDSRAI TLVTGSSRKI SVRLQRATTS QATQTEPVWS EAGWGDSGSH TFPKMKSKFH DKAAKDKGFA KWENEKPRVH AGVDVVDRGT EFELDQDEGE ETRQDGEDG
Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium and DAG-regulated guanine nucleotide exchange factor III; calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III; CalDAG-GEFIII; Guanine nucleotide exchange factor for Rap1; OTTHUMP00000201245; RAS guanyl releasing protein 3 (calcium and DAG-regulated); Ras guanyl-releasing protein 3
基因别名: BC066069; Gm327; GRP3; KIAA0846; RASGRP3
UniProt ID: (Human) Q8IV61
Entrez Gene ID: (Human) 25780, (Mouse) 240168
分子生物学功能: guanyl-nucleotide exchange factor