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RASSF2 Antibody (MA5-55545) in WB
Western Blot analysis of various lysates using RASSF2 Recombinant Monoclonal Antibody (Product # MA5-55545) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
MA5-55545
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5U1E0
抗原
A synthetic peptide corresponding to a sequence within amino acids 227-326 of human RASSF2.
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
Immunogen Sequence: HTSGEKQKLK ATDYPLIARI LQGPCEQISK VFLMEKDQVE EVTYDVAQYI KFEMPVLKSF IQKLQEEEDR EVKKLMRKYT VLRLMIRQRL EEIAETPATI
靶标信息
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centromere protein 34; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain-containing protein 2; RP4-599I11.1
基因别名: 3830431H01Rik; 9030412M04Rik; AI852669; AW495050; CENP-34; KIAA0168; RASFADIN; RASSF2
UniProt ID: (Human) A6NIX9, (Mouse) Q8BMS9, (Rat) Q3B7D5
Entrez Gene ID: (Human) 9770, (Mouse) 215653, (Rat) 311437
skeletal system development
ossification
protein phosphorylation
cell cycle
positive regulation of protein autophosphorylation
negative regulation of peptidyl-serine phosphorylation
epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade
positive regulation of apoptotic process
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein kinase activity
positive regulation of JNK cascade
bone remodeling
homeostasis of number of cells
protein stabilization
negative regulation of NIK/NF-kappaB signaling
signal transduction
regulation of NIK/NF-kappaB signaling
