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RBM15 Antibody (A300-821A) in WB
Detection of human and mouse RBM15 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-RBM15 antibody A300-821A (lot A300-821A-2) used for WB at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
产品信息
A300-821A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 550 and 600 of Human RNA Binding Motif Protein 15.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: one twenty two protein; one twenty-two; One-twenty two protein 1; RNA-binding motif protein 15; RNA-binding protein 15
基因别名: OTT; OTT1; RBM15; SPEN
UniProt ID: (Human) Q5T613
Entrez Gene ID: (Human) 64783
mRNA splicing, via spliceosome
patterning of blood vessels
positive regulation of transcription of Notch receptor target
viral process
negative regulation of myeloid cell differentiation
negative regulation of transcription, DNA-templated
spleen development
ventricular septum morphogenesis
placenta blood vessel development
