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Immunogen sequence: MAITQFRLF KFCTCLATVF SFLKRLICRS GRGRKLSGDQ ITLPTTVDYS SVPKQTDVEE WTSWDEDAPT SVKIEGGNGN VATQQNSLEQ LEPDYFKDMT PTIRKTQKIV IKKREPLNFG IPDGSTGFSS RLAATQDLPF IHQSSELGDL DTWQENTNAW EEEEDAAWQA EEVLRQQKLA DREKRAAEQQ RKKMEKEAQR LMKKEQNKIG VKLS (1-213 aa encoded by BC017729)
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BAG9; cancer associated surface antigen; cancer associated surface antigen RCAS1; Cancer-associated surface antigen RCAS1; estrogen receptor binding fragment associated gene 9; Estrogen receptor-binding fragment-associated gene 9 protein; HGNC:3123; receptor binding cancer antigen expressed on SiSo cells; Receptor-binding cancer antigen expressed on SiSo cells
基因别名: AI835379; EB9; EBAG9; PDAF; RCAS1
UniProt ID: (Human) O00559, (Mouse) Q9D0V7, (Rat) Q5PQP2
Entrez Gene ID: (Human) 9166, (Mouse) 55960, (Rat) 299864