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This is a rabbit polyclonal antibody raised against part of C-terminal of RECQ4 of human origin. The calculated molecular weight of EIF3B is 133 kDa, but the modified EIF3B protein is about 145-150 kDa.
Immunogen sequence: CTCTCTRPP SEQEGAVGGE RPVPKYPPQE AEQLSHQAAP GPRRVCMGHE RALPIQLTVQ ALDMPEEAIE TLLCYLELHP HHWLELLATT YTHCRLNCPG GPAQLQALAH RCPPLAVCLA QQLPEDPGQG SSSVEFDMVK LVDSMGWELA SVRRALCQLQ WDHEPRTGVR RGTGVLVEFS ELAFHLRSPG DLTAEEKDQI CDFLYGRVQA RERQALARLR RTFQAFHSVA FPSCGPCLEQ QDEERSTRLK DLLGRYFEEE EGQEPGGMED AQGPEPGQAR LQDWEDQVRC DIRQFLSLRP EEKFSSRAVA RIFHGIGSPC YPAQVYGQDR RFWRKYLHLS FHALVGLATE ELLQVAR (297-652 aa encoded by BC013277 )
The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent DNA helicase Q4; DNA 3'-5' helicase RecQ4; DNA helicase, RecQ-like type 4; DNA helicase, RecQ-like, type 4; RecQ helicase-like 4; RecQ protein-like 4; RecQ4; RTS
基因别名: RECQ4; RECQL4
UniProt ID: (Human) O94761
Entrez Gene ID: (Human) 9401