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The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. The mRNA of the human gene is abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at low levels in brain, placenta, liver, colon, and leukocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Regulator of G-protein signaling 5; RGS-5; RGS5; RP11-430G6.2
基因别名: MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129; RGS5
UniProt ID: (Human) O15539
Entrez Gene ID: (Human) 8490
分子生物学功能:
GTPase-activating protein