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Proteintech

ROD1 Polyclonal Antibody

7 篇参考文献

查看其他6个PTBP3抗体

说明书

实验方案

技术支持

货号 14027-1-AP

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150 µL

说明书

实验方案

技术支持

抗体检测数据 (8)

Application

ROD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 8

ROD1 Antibody (14027-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human lymphoma using 14027-1-AP (ROD1 antibody) at dilution of 1:100 (under 40x lens).

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产品信息

14027-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2400

查看5篇已发表文章 5篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫沉淀 (IP)

Assay-dependent

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ROD1 Fusion Protein Ag5172 (1-350 aa encoded by BC044585)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.13 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MDASPSPFS LPKKLNELSA RRGSDELLSS GIINGPFTMN SSTPSTANGN DSKKFKRDRP PCSPSRVLHL RKIPCDVTEA EIISLGLPFG KVTNLLMLKG KSQAFLEMAS EEAAVTMVNY YTPITPHLRS QPVYIQYSNH RELKTDNLPN QARAQAALQA VSAVQSGSLA LSGGPSNEGT VLPGQSPVLR IIIENLFYPV TLEVLHQIFS KFGTVLKIIT FTKNNQFQAL LQYADPVNAH YAKMALDGQN IYNACCTLRI DFSKLTSLNV KYNNDKSRDF TRLDLPTGDG QPSLEPPMAA AFGAPGIISS PYAGAAGFAP AIGFPQATGL SVPAVPGALG PLTITSSAVT G (1-350 aa encoded by BC044585)

靶标信息

This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

PTBP1-activated co-transcriptional splicing controls epigenetic status of pluripotent stem cells.

Molecular cell

Iannone C,Kainov Y,Zhuravskaya A,Hamid F,Nojima T,Makeyev EV

Thu Jan 19 00:00:00 UTC 2023

PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A-mediated cell cycle progression.

Cancer cell international

Chen Y,Ji Y,Liu S,Liu Y,Feng W,Jin L

Tue Jan 11 00:00:00 UTC 2022

PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway.

Cancer cell international

Wu Q,Zhang B,Li B,Cao X,Chen X,Xue Q

Thu Apr 14 00:00:00 UTC 2022

PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway.

Cancer cell international

Wu Q,Zhang B,Li B,Cao X,Chen X,Xue Q

Thu Apr 14 00:00:00 UTC 2022

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.

Cell research

Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y

Mon Oct 01 00:00:00 UTC 2018

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.

Cell research

Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y

Mon Oct 01 00:00:00 UTC 2018

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.

Cell research

Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y

Mon Oct 01 00:00:00 UTC 2018

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.

Cell research

Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y

Mon Oct 01 00:00:00 UTC 2018

Overexpression of ROD1 inhibits invasion of breast cancer cells by suppressing the translocation of β-catenin into the nucleus.

Oncology letters

Zhou Y,Zou H,Wu E,Huang L,Yin R,Mei Y,Zhu X

Wed Aug 01 00:00:00 UTC 2018

Overexpression of ROD1 inhibits invasion of breast cancer cells by suppressing the translocation of β-catenin into the nucleus.

Oncology letters

Zhou Y,Zou H,Wu E,Huang L,Yin R,Mei Y,Zhu X

Wed Aug 01 00:00:00 UTC 2018

生物信息学

蛋白别名: fission yeast differentiation regulator; Polypyrimidine tract-binding protein 3; regulator of differentiation (in S. pombe) 1; Regulator of differentiation 1; Rod1; ROD1 regulator of differentiation 1

基因别名: 5830471K22Rik; AA407443; AI462022; AW107884; C86549; PTBP3; ROD1

UniProt ID: (Human) O95758, (Mouse) Q8BHD7, (Rat) Q9Z118

Entrez Gene ID: (Human) 9991, (Mouse) 230257, (Rat) 83515

功能

nucleotide binding RNA binding poly(A) RNA binding nucleic acid binding

参与通路

mRNA processing RNA splicing cell differentiation negative regulation of RNA splicing erythrocyte maturation regulation of cell differentiation negative regulation of mRNA splicing, via spliceosome anatomical structure morphogenesis

ROD1 Polyclonal Antibody

ROD1 Antibody (14027-1-AP) in IHC (P)

产品信息

14027-1-AP

免疫印迹 (WB)

免疫组化 (IHC)

免疫组化（石蜡） (IHC (P))

免疫沉淀 (IP)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

产品详细信息

靶标信息

生物信息学

性能保障

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