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Immunogen sequence: MVFRRFVEV GRVAYVSFGP HAGKLVAIVD VIDQNRALVD GPCTQVRRQA MPFKCMQLTD FILKFPHSAH QKYVRQAWQK ADINTKWAAT RWAKKIEARE RKAKMTDFDR FKVMKAKKMR NRIIKNEVKK LQKAALLKAS PKKAPGTKGT AAAAAAAAAA AKVPAKKITA ASKKAPAQKV PAQKATGQKA APAPKAQKGQ KAPAQKAPAP KASGKKA (1-216 aa encoded by BC000606)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Aoki M., Diabetes 45:157-164(1996). Tanaka M., Biochem. Biophys. Res. Commun. 243:531-537(1998). Yoshihama M., Genome Res. 12:379-390(2002).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 60S ribosomal protein L14; CAG-ISL 7; Large ribosomal subunit protein eL14; MGC88594
基因别名: 3100001N19Rik; AA407502; AL022816; CAG-ISL-7; CTG-B33; hRL14; L14; RL14; RPL14
UniProt ID: (Human) P50914, (Mouse) Q9CR57
Entrez Gene ID: (Human) 9045, (Rat) 65043, (Mouse) 67115
分子生物学功能: ribosomal protein