Search Thermo Fisher Scientific
Specificity: The antibody binds to human NgR2 with a Kd of 2.3 nM and to rat NgR2 with a Kd of 0.48 nM (bivalent binding).
Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: NgR2; Nogo receptor-like 3; Nogo-66 receptor homolog 1; Nogo-66 receptor-related protein 2; Reticulon-4 receptor-like 2; RTN4RL2; rtn4rl2 {ECO:0000312|RGD:727797}
基因别名: NgR2; NGRH1; NGRL3; RTN4RL2
UniProt ID: (Human) Q86UN3, (Mouse) Q7M6Z0, (Rat) Q80WD1
Entrez Gene ID: (Human) 349667, (Mouse) 269295, (Rat) 311169