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Rab3A+Rab3B+Rab3C+Rab3D Antibody (BS-6180R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded rat heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with Rab3A+Rab3B+Rab3C+Rab3D Antibody Polyclonal Antibody, Unconjugated (bs-6180R) at 1:400 overnight at 4°C, followed by a conjugated second... View More
产品信息
BS-6180R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human Rab3A+Rab3B+Rab3C+Rab3D.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brain antigen RAB3B; glioblastoma overexpressed; GTP-binding protein Rab-3D; Rab3D upregulated with myeloid differentiation; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related protein Rab-3B; Ras-related protein Rab-3C; Ras-related protein Rab-3D; Ras-related small GTP binding protein 3A; small GTP-binding protein Rab3C
基因别名: 2610528C18Rik; 2700062I01Rik; 3110015B08Rik; 3110037E15Rik; AI850886; C130057E11Rik; D2-2; GOV; RAB16; RAB3; RAB3A; RAB3B; RAB3C; RAB3D; RAD3D
UniProt ID: (Human) P20336, (Human) P20337, (Human) Q96E17, (Human) O95716, (Rat) P63012, (Mouse) P63011, (Mouse) Q9CZT8, (Rat) Q63941, (Rat) P62824, (Mouse) P62823, (Mouse) P35276, (Rat) Q63942
Entrez Gene ID: (Human) 5864, (Human) 5865, (Human) 115827, (Human) 9545, (Rat) 25531, (Mouse) 19339, (Mouse) 69908, (Rat) 81755, (Rat) 171058, (Mouse) 67295, (Mouse) 19340, (Rat) 140665
small GTPase mediated signal transduction
protein transport
regulation of exocytosis
antigen processing and presentation
intracellular protein transport
vesicle docking involved in exocytosis
metabolic process
protein secretion
synaptic vesicle exocytosis
Rab protein signal transduction
protein localization to plasma membrane
respiratory system process
mitochondrion organization
neuromuscular synaptic transmission
axonogenesis
post-embryonic development
synaptic vesicle maturation
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
positive regulation of ATPase activity
synaptic vesicle recycling
regulation of short-term neuronal synaptic plasticity
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
positive regulation of regulated secretory pathway
transport
peptidyl-cysteine methylation
positive regulation of dopamine uptake involved in synaptic transmission
regulation of vesicle size
exocytosis
bone resorption
synaptic vesicle transport
evoked neurotransmitter secretion
regulation of long-term synaptic potentiation
neurotransmitter secretion
glutamate secretion
constitutive secretory pathway
positive regulation of exocytosis
