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产品信息
A300-281A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
N-terminus of Human ubiquitin-conjugating enzyme E2A.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Bovine and Rabbit
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
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生物信息学
蛋白别名: E2 ubiquitin-conjugating enzyme A; HR6A; RAD6 homolog A; Ubiquitin carrier protein A; ubiquitin conjugating enzyme E2A; Ubiquitin-conjugating enzyme E2 A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); ubiquitin-conjugating enzyme E2A, RAD6 homolog; ubiquitin-conjugating enzyme HR6A; Ubiquitin-protein ligase A
基因别名: HHR6A; HR6A; Mhr6a; MRXS30; MRXSN; RAD6A; UBC2; UBE2A
UniProt ID: (Human) P49459, (Mouse) Q9Z255
Entrez Gene ID: (Human) 7319, (Mouse) 22209
protein polyubiquitination
in utero embryonic development
DNA repair
postreplication repair
ubiquitin-dependent protein catabolic process
positive regulation of cell proliferation
response to UV
histone H2A ubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
maternal process involved in female pregnancy
protein K48-linked ubiquitination
protein K11-linked ubiquitination
cellular response to DNA damage stimulus
protein ubiquitination
histone ubiquitination
