Invitrogen

Relaxin 1 Monoclonal Antibody (351713)

产品信息

MA5-24094

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2B

分类

Monoclonal

类型

Antibody

克隆号

351713

抗原

E. coli-derived recombinant human Relaxin-1 Lys26-Cys185

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2609733

产品详细信息

This antibody detects the precursor form of human Relaxin-1 in direct ELISAs and Western blots. This antibody does not detect mature Relaxin-1 heterodimer. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Relaxin-2 precursor or rhRelaxin-3 precursor is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.

仅用于科研。不用于诊断过程。未经明确授权不得转售。