Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 2
S100 Antibody (500-2144) in IHC (PFA)
Immunohistochemistry: Human melanoma stained with Rabbit anti S100 antibody (Cat# 500-2144) at 1:300 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
产品信息
500-2144
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encoding human S100 protein
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with proprietary stabilizer
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: Melanoma or Schwannoma
Cellular location: Cytoplasmic.
靶标信息
S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Protein S100-A1; Protein S100-B; S 100; S-100 calcium-binding protein, beta chain; S-100 protein alpha chain; S-100 protein beta chain; S-100 protein subunit alpha; S-100 protein subunit beta; S100 alpha; S100 calcium-binding protein A1; S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S100 protein, alpha polypeptide; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100alpha
基因别名: AI266795; AI850290; Bpb; NEF; S100; S100-alpha; S100-B; S100A; S100A1; S100B; S100beta; S100P
UniProt ID: (Bovine) P02639, (Human) P23297, (Human) P04271, (Bovine) P02638, (Rat) P35467, (Mouse) P56565, (Mouse) P50114, (Rat) P04631
Entrez Gene ID: (Bovine) 528735, (Human) 6271, (Human) 6285, (Bovine) 525716, (Rat) 295214, (Mouse) 20193, (Mouse) 20203, (Rat) 25742
calcium ion binding
protein binding
identical protein binding
protein homodimerization activity
S100 protein binding
calcium-dependent protein binding
ATPase binding
zinc ion binding
tau protein binding
RAGE receptor binding
kinase inhibitor activity
metal ion binding
receptor binding
calmodulin-related
negative regulation of transcription from RNA polymerase II promoter
regulation of heart contraction
substantia nigra development
intracellular signal transduction
positive regulation of voltage-gated calcium channel activity
axonogenesis
central nervous system development
learning or memory
memory
cell proliferation
positive regulation of cell proliferation
regulation of cell shape
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of neuronal synaptic plasticity
astrocyte differentiation
response to glucocorticoid
response to methylmercury
long-term synaptic potentiation
cellular response to hypoxia
negative regulation of skeletal muscle cell differentiation
regulation of translation
phosphorylation
negative regulation of kinase activity
positive regulation of complement activation
astrocyte activation
negative regulation of monocyte chemotactic protein-1 production
energy reserve metabolic process
cellular calcium ion homeostasis
regulation of cytokine biosynthetic process
regulation of long-term neuronal synaptic plasticity
positive regulation of synaptic transmission
