Proteintech

S100A11 Polyclonal Antibody

S100A11 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 23

S100A11 Antibody (10237-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed PC-3 cells using S100A11 antibody (Product # 10237-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

S100A11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

S100A11 Antibody in Flow Cytometry (Flow)

S100A11 Antibody in Immunoprecipitation (IP)

Product Image Gallery

产品信息

10237-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

查看30篇已发表文章 30篇已发表文章

免疫组化 (IHC)

查看13篇已发表文章 13篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

1:400

查看12篇已发表文章 12篇已发表文章

流式细胞分析 (Flow)

0.2 µg/1x10^6 cells

免疫沉淀 (IP)

0.5-4.0 µg

查看2篇已发表文章 2篇已发表文章

其他PubMed (Misc)

查看2篇已发表文章 2篇已发表文章

不适用 (N/A)

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

S100A11 Fusion Protein Ag0343 (3-105 aa encoded by BC001410)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.46 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

This S100A11 antibody (10237-1-AP) has also been instrumental in investigations into S100A11's role in the development of brain tumors in tuberous sclerosis complex (TSC) patients.

Immunogen sequence: KISSPTETE RCIESLIAVF QKYAGKDGYN YTLSKTEFLS FMNTELAAFT KNQKDPGVLD RMMKKLDTNS DGQLDFSEFL NLIGGLAMAC HDSFLKAVPS QKRT (3-105 aa encoded by BC001410)

靶标信息

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Association between serum S100A11 levels and glucose metabolism in diabetic process.

Diabetology & metabolic syndrome

Wu Y,Wu S,Li F,Zeng T,Luo X

Mon Mar 06 00:00:00 EST 2023

S100A11 Promotes Metastasis via AKT and ERK Signaling Pathways and Has a Diagnostic Role in Hepatocellular Carcinoma.

International journal of medical sciences

Zheng M,Meng H,Li Y,Shi J,Han Y,Zhao C,Chen J,Han J,Liang J,Chen Y,Liu Q,Wang Y

Fri Mar 03 00:00:00 EST 2023

S100A11 Promotes Metastasis via AKT and ERK Signaling Pathways and Has a Diagnostic Role in Hepatocellular Carcinoma.

International journal of medical sciences

Zheng M,Meng H,Li Y,Shi J,Han Y,Zhao C,Chen J,Han J,Liang J,Chen Y,Liu Q,Wang Y

Fri Mar 03 00:00:00 EST 2023

Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.

Aging

Shi X,Wu Y,Tang L,Ni H,Xu Y

Tue Mar 28 00:00:00 EDT 2023

The resealing factor S100A11 interacts with annexins and extended synaptotagmin-1 in the course of plasma membrane wound repair.

Frontiers in cell and developmental biology

Ashraf APK,Gerke V

Fri Oct 07 00:00:00 EDT 2022

S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.

Technology in cancer research & treatment

Wang H,Yin M,Ye L,Gao P,Mao X,Tian X,Xu Z,Dai X,Cheng H

Mon Nov 29 00:00:00 EST 2021

S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.

Cellular and molecular gastroenterology and hepatology

Zhang L,Zhang Z,Li C,Zhu T,Gao J,Zhou H,Zheng Y,Chang Q,Wang M,Wu J,Ran L,Wu Y,Miao H,Zou X,Liang B

Mon Dec 20 00:00:00 EST 2021

S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.

Cellular and molecular gastroenterology and hepatology

Zhang L,Zhang Z,Li C,Zhu T,Gao J,Zhou H,Zheng Y,Chang Q,Wang M,Wu J,Ran L,Wu Y,Miao H,Zou X,Liang B

Mon Dec 20 00:00:00 EST 2021

S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.

Cellular and molecular gastroenterology and hepatology

Zhang L,Zhang Z,Li C,Zhu T,Gao J,Zhou H,Zheng Y,Chang Q,Wang M,Wu J,Ran L,Wu Y,Miao H,Zou X,Liang B

Mon Dec 20 00:00:00 EST 2021

Plasma membrane wound repair is characterized by extensive membrane lipid and protein rearrangements in vascular endothelial cells.

Biochimica et biophysica acta. Molecular cell research

Ashraf APK,Gerke V

Tue Jun 01 00:00:00 EDT 2021

ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells.

Cell & bioscience

Wang K,Chen H,Zhou Z,Zhang H,Zhou HJ,Min W

Sat Jan 09 00:00:00 EST 2021

CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity.

iScience

Dias C,Nita E,Faktor J,Tynan AC,Hernychova L,Vojtesek B,Nylandsted J,Hupp TR,Kunath T,Ball KL

Fri Aug 20 00:00:00 EDT 2021

The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.

Metabolism: clinical and experimental

Teng F,Jiang J,Zhang J,Yuan Y,Li K,Zhou B,Zhou X,Liu W,Zhang P,Liu D,Zheng M,Lu Y,Zhang H

Thu Apr 01 00:00:00 EDT 2021

Electroacupuncture Promoted Nerve Repair After Peripheral Nerve Injury by Regulating miR-1b and Its Target Brain-Derived Neurotrophic Factor.

Frontiers in neuroscience

Liu YP,Luo ZR,Wang C,Cai H,Zhao TT,Li H,Shao SJ,Guo HD

Tue Nov 03 00:00:00 EST 2020

Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11.

American journal of physiology. Cell physiology

Katsumi T,Guicciardi ME,Azad A,Bronk SF,Krishnan A,Gores GJ

Tue Oct 01 00:00:00 EDT 2019

Proteomics analysis of the matrisome from MC38 experimental mouse liver metastases.

American journal of physiology. Gastrointestinal and liver physiology

Yuzhalin AE,Lim SY,Gordon-Weeks AN,Fischer R,Kessler BM,Yu D,Muschel RJ

Fri Nov 01 00:00:00 EDT 2019

Annexin A7 is required for ESCRT III-mediated plasma membrane repair.

Scientific reports

Sønder SL,Boye TL,Tölle R,Dengjel J,Maeda K,Jäättelä M,Simonsen AC,Jaiswal JK,Nylandsted J

Tue Apr 30 00:00:00 EDT 2019

S100 Calcium Binding Protein A11 (S100A11) Promotes The Proliferation, Migration And Invasion Of Cervical Cancer Cells, And Activates Wnt/β-Catenin Signaling.

OncoTargets and therapy

Meng M,Sang L,Wang X

Mon Apr 11 00:00:00 EDT 2022

S100 Calcium Binding Protein A11 (S100A11) Promotes The Proliferation, Migration And Invasion Of Cervical Cancer Cells, And Activates Wnt/β-Catenin Signaling.

OncoTargets and therapy

Meng M,Sang L,Wang X

Mon Apr 11 00:00:00 EDT 2022

Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma.

Oncogenesis

Sato H,Sakaguchi M,Yamamoto H,Tomida S,Aoe K,Shien K,Yoshioka T,Namba K,Torigoe H,Soh J,Tsukuda K,Tao H,Okabe K,Miyoshi S,Pass HI,Toyooka S

Wed Jan 24 00:00:00 EST 2018

Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma.

Oncogenesis

Sato H,Sakaguchi M,Yamamoto H,Tomida S,Aoe K,Shien K,Yoshioka T,Namba K,Torigoe H,Soh J,Tsukuda K,Tao H,Okabe K,Miyoshi S,Pass HI,Toyooka S

Wed Jan 24 00:00:00 EST 2018

Defective interplay between mTORC1 activity and endoplasmic reticulum stress-unfolded protein response in uremic vascular calcification.

American journal of physiology. Renal physiology

Panda DK,Bai X,Sabbagh Y,Zhang Y,Zaun HC,Karellis A,Koromilas AE,Lipman ML,Karaplis AC

Fri Jun 01 00:00:00 EDT 2018

Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis.

Arthritis research & therapy

Andrés Cerezo L,Šumová B,Prajzlerová K,Veigl D,Damgaard D,Nielsen CH,Pavelka K,Vencovský J,Šenolt L

Wed Apr 26 00:00:00 EDT 2017

Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis.

Arthritis research & therapy

Andrés Cerezo L,Šumová B,Prajzlerová K,Veigl D,Damgaard D,Nielsen CH,Pavelka K,Vencovský J,Šenolt L

Wed Apr 26 00:00:00 EDT 2017

Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis.

Arthritis research & therapy

Andrés Cerezo L,Šumová B,Prajzlerová K,Veigl D,Damgaard D,Nielsen CH,Pavelka K,Vencovský J,Šenolt L

Wed Apr 26 00:00:00 EDT 2017

Knockdown of BC200 RNA expression reduces cell migration and invasion by destabilizing mRNA for calcium-binding protein S100A11.

RNA biology

Shin H,Lee J,Kim Y,Jang S,Lee Y,Kim S,Lee Y

Tue Oct 03 00:00:00 EDT 2017

Knockdown of BC200 RNA expression reduces cell migration and invasion by destabilizing mRNA for calcium-binding protein S100A11.

RNA biology

Shin H,Lee J,Kim Y,Jang S,Lee Y,Kim S,Lee Y

Tue Oct 03 00:00:00 EDT 2017

Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells.

Oncology letters

Subhasitanont P,Chokchaichamnankit D,Chiablaem K,Keeratichamroen S,Ngiwsara L,Paricharttanakul NM,Lirdprapamongkol K,Weeraphan C,Svasti J,Srisomsap C

Sun Oct 01 00:00:00 EDT 2017

Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells.

Oncology letters

Subhasitanont P,Chokchaichamnankit D,Chiablaem K,Keeratichamroen S,Ngiwsara L,Paricharttanakul NM,Lirdprapamongkol K,Weeraphan C,Svasti J,Srisomsap C

Sun Oct 01 00:00:00 EDT 2017

Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport.

Developmental cell

Eden ER,Sanchez-Heras E,Tsapara A,Sobota A,Levine TP,Futter CE

Mon Jun 06 00:00:00 EDT 2016

Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport.

Developmental cell

Eden ER,Sanchez-Heras E,Tsapara A,Sobota A,Levine TP,Futter CE

Mon Jun 06 00:00:00 EDT 2016

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

Cell cycle (Georgetown, Tex.)

Foertsch F,Szambowska A,Weise A,Zielinski A,Schlott B,Kraft F,Mrasek K,Borgmann K,Pospiech H,Grosse F,Melle C

Mon Oct 17 00:00:00 EDT 2016

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

Cell cycle (Georgetown, Tex.)

Foertsch F,Szambowska A,Weise A,Zielinski A,Schlott B,Kraft F,Mrasek K,Borgmann K,Pospiech H,Grosse F,Melle C

Mon Oct 17 00:00:00 EDT 2016

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

Cell cycle (Georgetown, Tex.)

Foertsch F,Szambowska A,Weise A,Zielinski A,Schlott B,Kraft F,Mrasek K,Borgmann K,Pospiech H,Grosse F,Melle C

Mon Oct 17 00:00:00 EDT 2016

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

Cell cycle (Georgetown, Tex.)

Foertsch F,Szambowska A,Weise A,Zielinski A,Schlott B,Kraft F,Mrasek K,Borgmann K,Pospiech H,Grosse F,Melle C

Mon Oct 17 00:00:00 EDT 2016

Imaging mass spectrometry for accessing molecular changes during burn wound healing.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Taverna D,Pollins AC,Sindona G,Caprioli RM,Nanney LB

Thu Sep 01 00:00:00 EDT 2016

Imaging mass spectrometry for accessing molecular changes during burn wound healing.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Taverna D,Pollins AC,Sindona G,Caprioli RM,Nanney LB

Thu Sep 01 00:00:00 EDT 2016

S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.

Nature communications

Jaiswal JK,Lauritzen SP,Scheffer L,Sakaguchi M,Bunkenborg J,Simon SM,Kallunki T,Jäättelä M,Nylandsted J

Thu May 08 00:00:00 EDT 2014

S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.

Nature communications

Jaiswal JK,Lauritzen SP,Scheffer L,Sakaguchi M,Bunkenborg J,Simon SM,Kallunki T,Jäättelä M,Nylandsted J

Thu May 08 00:00:00 EDT 2014

S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.

Nature communications

Jaiswal JK,Lauritzen SP,Scheffer L,Sakaguchi M,Bunkenborg J,Simon SM,Kallunki T,Jäättelä M,Nylandsted J

Thu May 08 00:00:00 EDT 2014

S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.

Nature communications

Jaiswal JK,Lauritzen SP,Scheffer L,Sakaguchi M,Bunkenborg J,Simon SM,Kallunki T,Jäättelä M,Nylandsted J

Thu May 08 00:00:00 EDT 2014

S100A11 is involved in the regulation of the stability of cell cycle regulator p21(CIP1/WAF1) in human keratinocyte HaCaT cells.

The FEBS journal

Foertsch F,Teichmann N,Kob R,Hentschel J,Laubscher U,Melle C

Thu Aug 01 00:00:00 EDT 2013

S100A11 is involved in the regulation of the stability of cell cycle regulator p21(CIP1/WAF1) in human keratinocyte HaCaT cells.

The FEBS journal

Foertsch F,Teichmann N,Kob R,Hentschel J,Laubscher U,Melle C

Thu Aug 01 00:00:00 EDT 2013

S100A11 is a migration-related protein in laryngeal squamous cell carcinoma.

International journal of medical sciences

Wang C,Zhang Z,Li L,Zhang J,Wang J,Fan J,Jiao B,Zhao S

Fri Apr 11 00:00:00 EDT 2014

S100A11 is a migration-related protein in laryngeal squamous cell carcinoma.

International journal of medical sciences

Wang C,Zhang Z,Li L,Zhang J,Wang J,Fan J,Jiao B,Zhao S

Fri Apr 11 00:00:00 EDT 2014

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.

Biochimica et biophysica acta

Poeter M,Radke S,Koese M,Hessner F,Hegemann A,Musiol A,Gerke V,Grewal T,Rescher U

Mon Jul 01 00:00:00 EDT 2013

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.

Biochimica et biophysica acta

Poeter M,Radke S,Koese M,Hessner F,Hegemann A,Musiol A,Gerke V,Grewal T,Rescher U

Mon Jul 01 00:00:00 EDT 2013

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.

Biochimica et biophysica acta

Poeter M,Radke S,Koese M,Hessner F,Hegemann A,Musiol A,Gerke V,Grewal T,Rescher U

Mon Jul 01 00:00:00 EDT 2013

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.

Biochimica et biophysica acta

Poeter M,Radke S,Koese M,Hessner F,Hegemann A,Musiol A,Gerke V,Grewal T,Rescher U

Mon Jul 01 00:00:00 EDT 2013

Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.

The Journal of pathology

Meding S,Balluff B,Elsner M,Schöne C,Rauser S,Nitsche U,Maak M,Schäfer A,Hauck SM,Ueffing M,Langer R,Höfler H,Friess H,Rosenberg R,Walch A

Sat Dec 01 00:00:00 EST 2012

Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.

The Journal of pathology

Meding S,Balluff B,Elsner M,Schöne C,Rauser S,Nitsche U,Maak M,Schäfer A,Hauck SM,Ueffing M,Langer R,Höfler H,Friess H,Rosenberg R,Walch A

Sat Dec 01 00:00:00 EST 2012

Down-regulation of S100A11, a calcium-binding protein, in human endometrium may cause reproductive failure.

The Journal of clinical endocrinology and metabolism