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Invitrogen
S100B Monoclonal Antibody (CL2720)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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S100B Antibody (MA5-34997) in IHC (P)
Immunohistochemical analysis of S100B was performed using formalin-fixed paraffin-embedded mouse brain and mouse thymus tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for... View More
产品信息
MA5-34997
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL2720
抗原
Recombinant Protein corresonding to Human S100B
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2848902
产品详细信息
Immunogen sequence: LEKAMVALID VFHQYSGREG DKHKLKKSEL KELINNELSH FLEEIKEQEV VDKVMETLDN DGDGECDFQE FMAFVAMVTT ACHEFFEHE
靶标信息
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein S100-B; S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S100 protein beta chain; S100 protein, beta polypeptide, neural
基因别名: AI850290; Bpb; NEF; S100; S100-B; S100B; S100beta; S100P
UniProt ID: (Human) P04271, (Mouse) P50114, (Rat) P04631
Entrez Gene ID: (Human) 6285, (Mouse) 20203, (Rat) 25742
axonogenesis
central nervous system development
learning or memory
memory
cell proliferation
positive regulation of cell proliferation
regulation of cell shape
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of neuronal synaptic plasticity
astrocyte differentiation
response to glucocorticoid
response to methylmercury
long-term synaptic potentiation
cellular response to hypoxia
negative regulation of skeletal muscle cell differentiation
energy reserve metabolic process
cellular calcium ion homeostasis
regulation of cytokine biosynthetic process
regulation of long-term neuronal synaptic plasticity
positive regulation of synaptic transmission
