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Immunogen sequence: MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK; Positive Samples: SW480, HeLa, Mouse small intestine, Rat small intestine; Cellular Location: Cell projection, Cytoplasm, Nucleus, microvillus membrane
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MIG9; Migration-inducing gene 9 protein; Protein S100-E; Protein S100-P; S100 calcium binding protein P; S100 calcium-binding protein P
基因别名: MIG9; S100E; S100P
UniProt ID: (Human) P25815
Entrez Gene ID: (Human) 6286, (Rat) 103693162
分子生物学功能: calmodulin-related