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STAG2 is a component of the cohesin complex. This complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cohesin subunit SA-2; DKFZp686P168; DKFZp781H1753; FLJ25871; nuclear protein SA2; OTTHUMP00000024338; OTTHUMP00000043514; OTTHUMP00000043515; OTTHUMP00000081754; OTTHUMP00000081755; RP11-517O1.1; SCC3 homolog 2; Stromal antigen 2
基因别名: 9230105L23Rik; B230112I07Rik; bA517O1.1; SA-2; SA2; SAP2; SCC3B; STAG2
UniProt ID: (Human) Q8N3U4, (Mouse) O35638
Entrez Gene ID: (Human) 10735, (Mouse) 20843