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产品信息
H00006288-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3C11-2C1
抗原
SAA1 (AAH07022, 1 a.a. approximately 122 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: MKLLTGLVFC SLVLGVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY DAAKRGPGGV WAAEAISDAR ENIQRFFGHG AEDSLADQAA DEWGRSGKDP NHFRPAGLPE KY
靶标信息
The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amyloid a; MGC111216; SAA; serum amyloid A protein; Serum amyloid A-1 protein; Serum amyloid A1 protein; Serum Amyloid-A; tumor protein p53 inducible protein 4
基因别名: PIG4; SAA; SAA1; SAA2; TP53I4
UniProt ID: (Human) P0DJI8
Entrez Gene ID: (Human) 6288
activation of MAPK activity
receptor-mediated endocytosis
acute-phase response
positive regulation of cytosolic calcium ion concentration
platelet activation
neutrophil chemotaxis
cellular protein metabolic process
innate immune response
positive regulation of cell adhesion
macrophage chemotaxis
lymphocyte chemotaxis
regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of interleukin-1 secretion
negative regulation of inflammatory response
positive chemotaxis
