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SAE1 Antibody (MA5-42632) in WB
Western blot analysis of SAE1 in extracts of various cell lines. Samples were incubated with SAE1 Monoclonal antibody (Product # MA5-42632) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
MA5-42632
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
0L2N2
抗原
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SAE1 (Q9UBE0).
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911773
产品详细信息
Positive test controls include: 293T, MCF7, DU145, Mouse testis, Mouse thymus, Rat testis. The target is usually found in the following locations: Nucleus.
Immunogen sequence: DSSETTMVKK KVVFCPVKEA LEVDWSSEKA KAALKRTTSD YFLLQVLLKF RTDKGRDPSS DTYEEDSELL LQIRNDVLDS LGISPDLLPE DFVRYCFSEM A
靶标信息
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2. form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activator of SUMO1; FLJ3091; sentrin/SUMO-activating protein AOS1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; ubiquitin-like (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme
基因别名: 2400010M20Rik; 2610044L12Rik; AL033372; AOS1; AW743391; D7Ertd177e; HSPC140; SAE1; SUA1; Ubl1a1; UBLE1A
UniProt ID: (Human) Q9UBE0, (Mouse) Q9R1T2, (Rat) Q6AXQ0
Entrez Gene ID: (Human) 10055, (Mouse) 56459, (Rat) 308384
