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Store as concentrated solution.
Centrifuge briefly prior to opening vial.
ORF9b plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1/DNM1L.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COVID-19 ORF9b; COVID19 ORF9b; ORF9b; SARS-CoV-2 Open Reading Frame 9b; SARS-COV2 ORF9b