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Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS
Predicted Reactivity: Xenopus laevis (81%), Chicken (90%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: collapsin 1; collapsin-1; MGC133243; Sema D; sema domain, immunoglobulin domain (Ig), short basic domain, sec; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; Sema III; Semaphorin 3a; semaphorin D; Semaphorin III; semaphorin L; Semaphorin-3A; Semaphorin-D
基因别名: coll-1; COLL1; HH16; Hsema-I; Hsema-III; SEMA1; SEMA3A; SEMAD; SEMAIII; SEMAL; SemD
UniProt ID: (Human) Q14563, (Mouse) Q62215, (Rat) Q63548
Entrez Gene ID: (Human) 10371, (Mouse) 20346, (Rat) 29751