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产品信息
PA5-52788
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2647110
产品详细信息
Immunogen sequence: VDGELYSATL NNFLGTEPII LRNMGPHHSM KTEYLAFWLN EPHFVGSAYV PESVGSFTGD DDKVYFFFRE RAVESDCYAE QVVARVARVC KGDMGGARTL QRKWTTFLKA RLACSAPNWQ LYF
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
靶标信息
SEMA4C (semaphorin-4C), also known as SEMAF, is an 833 amino acid single-pass type I membrane protein that contains one sema domain, one PSI domain and one Ig-like C2-type domain. Expressed in a variety of tissues, including lung, kidney and brain, SEMA4C interacts with GIPC and NCDN and is thought to play a role in the formation of neural networks during development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ20369; M-Sema F; MGC126382; MGC126383; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; Semaphorin-4C
基因别名: KIAA1739; M-SEMA-F; SEMA4C; SEMACL1; SEMAF; SEMAI; UNQ5855/PRO34487
UniProt ID: (Human) Q9C0C4
Entrez Gene ID: (Human) 54910
neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway
