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Immunogen sequence: FAFIHKDFDV KETFFNLSKR YFDTECVPMN FRNASQAKRL MNHYINKETR GKIPKLFDEI NPETKLILVD YILFKGKWLT PFDPVFTEVD TFHLDKYKTI KVPMMYGAGK FASTFDKNFR CHVLKLPYQG NATMLVVLME KMGDHLALED YLTTDLVETW LRNMKTRNME VFFPKFKLDQ KYEMHELLRQ MGIRRIFSPF ADLSELSATG RNLQVSRVLQ RTVIEVDERG TEAVAGILSE ITAYSMPPVI KVDRPFHFMI YEETSGMLLF LGRVVNPTLL
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: plasma protein associated with liver regeneration; Protein Z-dependent protease inhibitor; PZ-dependent protease inhibitor; PZI; RASP-1; Regeneration-associated serpin 1; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; Serpin A10; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serpin peptidase inhibitor, clade A, member 10
基因别名: PZI; Rasp1; SERPINA10; UNQ707/PRO1358; ZPI
UniProt ID: (Human) Q9UK55, (Rat) Q62975, (Mouse) Q8R121
Entrez Gene ID: (Human) 51156, (Rat) 171154, (Mouse) 217847
分子生物学功能:
protease inhibitor