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SETDB2 Antibody (PA5-110357) in WB
Western blot analysis of SETDB2 in extracts of various cell lines. Samples were incubated with SETDB2 Polyclonal antibody (Product # PA5-110357) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110357
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 148-378 of human SETDB2 (NP_1141212)
偶联物
形式
Liquid
浓度
1.04 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855768
产品详细信息
Immunogen sequence: SGACLMKMPL NLKGENPLQL PIKCHFQRRH AKTNSHSSAL HVSYKTPCGR SLRNVEEVFR YLLETECNFL FTDNFSFNTY VQLARNYPKQ KEVVSDVDIS NGVESVPISF CNEIDSRKLP QFKYRKTVWP RAYNLTNFSS MFTDSCDCSE GCIDITKCAC LQLTARNAKT SPLSSDKITT GYKYKRLQRQ IPTGIYECSL LCKCNRQLCQ NRVVQHGPQV RLQVFKTEQK G
靶标信息
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bifurcated 2; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; histone-lysine N-methyltransferase SETDB2; SET domain; Setdb2-Phf11-1-Phf11-2 fusion
基因别名: Clld8; Gm293; KMT1F
Entrez Gene ID: (Mouse) 239122
