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SGEF Antibody (PA5-109410) in WB
Western blot analysis of SGEF in extracts of various cell lines. Samples were incubated with SGEF Polyclonal antibody (Product # PA5-109410) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-109410
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3).
偶联物
形式
Liquid
浓度
1.75 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2854821
产品详细信息
Immunogen sequence: ICQKTPKDSP KYEVCKRALK EVSKLVRLCN EGARKMERTE MMYTINSQLE FKIKPFPLVS SSRWLVKRGE LTAYVEDTVL FSRRTSKQQV YFFLFNDVLI ITKKKSEESY NVNDYSLRDQ LLVESCDNEE LNSSPGKNSS TMLYSRQSSA SHLFTLTVLS NHANEKVEML LGAETQSERA RWITALGHSS GKPPADRTSL TQVEIVRSFT AKQPDELSLQ VADVVLIYQR VSDGWYEGER LRDGERGWFP MECAKEITCQ ATIDKNVERM GRLLGLETNV
靶标信息
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Rho guanine nucleotide exchange factor (GEF) 26; Rho guanine nucleotide exchange factor 26; SH3 domain-containing guanine exchange factor; Src homology 3 domain-containing guanine nucleotide exchange factor; testicular tissue protein Li 171
基因别名: 4631416L12Rik; 8430436L14Rik; AI303572; ARHGEF26; AW491953; CSGEF; HMFN1864; RGD1562559; SGEF
UniProt ID: (Human) Q96DR7
Entrez Gene ID: (Human) 26084, (Mouse) 622434, (Rat) 310460
