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Sequence of this protein is as follows: SPINWDDLYH KRLTPPFNPN VTGPADLKHF DPEFTQEAVS KSIGCTPDTV ASSSGASSAF LGFSYAPEDD DILDC
SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; Serum/glucocorticoid-regulated kinase 2
基因别名: AI098171; AW146006; dJ138B7.2; H-SGK2; SGK2; Sgkl
UniProt ID: (Human) Q9HBY8, (Mouse) Q9QZS5
Entrez Gene ID: (Human) 10110, (Mouse) 27219