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Proteintech

SH2D1B Polyclonal Antibody

10 篇参考文献

查看其他6个SH2D1B抗体

说明书

实验方案

技术支持

货号 11871-1-AP

此产品在中国无法购买

150 µL

说明书

实验方案

技术支持

抗体检测数据 (9)

Application

SH2D1B Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 9

SH2D1B Antibody (11871-1-AP) in ICC/IF

Immunofluorescent analysis of (-20&(8)451; Ethanol) fixed HepG2 cells using (Product # 11871-1-AP) (SH2D1B antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

SH2D1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SH2D1B Antibody in Flow Cytometry (Flow)

Product Image Gallery

产品信息

11871-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

1:50

流式细胞分析 (Flow)

0.2 µg/1x10^6 cells

查看4篇已发表文章 4篇已发表文章

免疫沉淀 (IP)

Assay-dependent

查看1篇已发表文章 1篇已发表文章

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

不适用 (N/A)

查看3篇已发表文章 3篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

SH2D1B Fusion Protein Ag2454 (1-132 aa encoded by BC022407)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.37 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MDLPYYHGR LTKQDCETLL LKEGVDGNFL LRDSESIPGV LCLCVSFKNI VYTYRIFREK HGYYRIQTAE GSPKQVFPSL KELISKFEKP NQGMVVHLLK PIKRTSPSLR WRGLKLELET FVNSNSDYVD VLP (1-132 aa encoded by BC022407)

靶标信息

SH2D1B plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Anti-NKG2C/IL-15/anti-CD33 killer engager directs primary and iPSC-derived NKG2C⁺ NK cells to target myeloid leukemia.

Molecular therapy : the journal of the American Society of Gene Therapy

Chiu E,Felices M,Cichocki F,Davis Z,Wang H,Tuninga K,Vallera DA,Lee T,Bjordahl R,Malmberg KJ,Valamehr B,Miller JS

Wed Dec 01 00:00:00 UTC 2021

Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection.

Frontiers in immunology

Gyurova IE,Schlums H,Sucharew H,Ambroggio L,Ochayon DE,Win HT,Bryceson YT,Bernstein DI,Waggoner SN

Fri Nov 06 00:00:00 UTC 2020

ARID5B regulates metabolic programming in human adaptive NK cells.

The Journal of experimental medicine

Cichocki F,Wu CY,Zhang B,Felices M,Tesi B,Tuininga K,Dougherty P,Taras E,Hinderlie P,Blazar BR,Bryceson YT,Miller JS

Mon Sep 03 00:00:00 UTC 2018

ARID5B regulates metabolic programming in human adaptive NK cells.

The Journal of experimental medicine

Cichocki F,Wu CY,Zhang B,Felices M,Tesi B,Tuininga K,Dougherty P,Taras E,Hinderlie P,Blazar BR,Bryceson YT,Miller JS

Mon Sep 03 00:00:00 UTC 2018

T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.

Journal of immunology (Baltimore, Md. : 1950)

Radomir L,Cohen S,Kramer MP,Bakos E,Lewinsky H,Barak A,Porat Z,Bucala R,Stepensky P,Becker-Herman S,Shachar I

Sun Oct 15 00:00:00 UTC 2017

T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.

Journal of immunology (Baltimore, Md. : 1950)

Radomir L,Cohen S,Kramer MP,Bakos E,Lewinsky H,Barak A,Porat Z,Bucala R,Stepensky P,Becker-Herman S,Shachar I

Sun Oct 15 00:00:00 UTC 2017

T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.

Journal of immunology (Baltimore, Md. : 1950)

Radomir L,Cohen S,Kramer MP,Bakos E,Lewinsky H,Barak A,Porat Z,Bucala R,Stepensky P,Becker-Herman S,Shachar I

Sun Oct 15 00:00:00 UTC 2017

T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.

Journal of immunology (Baltimore, Md. : 1950)

Radomir L,Cohen S,Kramer MP,Bakos E,Lewinsky H,Barak A,Porat Z,Bucala R,Stepensky P,Becker-Herman S,Shachar I

Sun Oct 15 00:00:00 UTC 2017

Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals.

Immunity

Lee J,Zhang T,Hwang I,Kim A,Nitschke L,Kim M,Scott JM,Kamimura Y,Lanier LL,Kim S

Tue Mar 17 00:00:00 UTC 2015

Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals.

Immunity

Lee J,Zhang T,Hwang I,Kim A,Nitschke L,Kim M,Scott JM,Kamimura Y,Lanier LL,Kim S

Tue Mar 17 00:00:00 UTC 2015

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function.

Immunity

Schlums H,Cichocki F,Tesi B,Theorell J,Beziat V,Holmes TD,Han H,Chiang SC,Foley B,Mattsson K,Larsson S,Schaffer M,Malmberg KJ,Ljunggren HG,Miller JS,Bryceson YT

Tue Mar 17 00:00:00 UTC 2015

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function.

Immunity

Schlums H,Cichocki F,Tesi B,Theorell J,Beziat V,Holmes TD,Han H,Chiang SC,Foley B,Mattsson K,Larsson S,Schaffer M,Malmberg KJ,Ljunggren HG,Miller JS,Bryceson YT

Tue Mar 17 00:00:00 UTC 2015

Systemic lupus erythematosus immune complexes increase the expression of SLAM family members CD319 (CRACC) and CD229 (LY-9) on plasmacytoid dendritic cells and CD319 on CD56(dim) NK cells.

Journal of immunology (Baltimore, Md. : 1950)

Hagberg N,Theorell J,Schlums H,Eloranta ML,Bryceson YT,Rönnblom L

Sun Sep 15 00:00:00 UTC 2013

Systemic lupus erythematosus immune complexes increase the expression of SLAM family members CD319 (CRACC) and CD229 (LY-9) on plasmacytoid dendritic cells and CD319 on CD56(dim) NK cells.

Journal of immunology (Baltimore, Md. : 1950)

Hagberg N,Theorell J,Schlums H,Eloranta ML,Bryceson YT,Rönnblom L

Sun Sep 15 00:00:00 UTC 2013

生物信息学

蛋白别名: EAT-2; EWS/FLI1 activated transcript 2; EWS/FLI1-activated transcript 2; SH2 domain containing 1B; SH2 domain protein 1B1; SH2 domain-containing molecule EAT2; SH2 domain-containing protein 1B

基因别名: EAT-2; EAT-2A; EAT2; Eat2a; RGD1563935; SH2D1B; Sh2d1b1

UniProt ID: (Human) O14796

Entrez Gene ID: (Human) 117157, (Rat) 501869, (Mouse) 26904

功能

protein binding protein binding, bridging phosphotyrosine binding molecular_function signaling adaptor activity

参与通路

adaptive immune response leukocyte activation involved in immune response positive regulation of natural killer cell mediated immunity innate immune response positive regulation of innate immune response regulation of immune response natural killer cell inhibitory signaling pathway positive regulation of signal transduction peptidyl-tyrosine phosphorylation negative regulation of interferon-gamma production negative regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity positive regulation of peptidyl-tyrosine phosphorylation negative regulation of peptidyl-tyrosine phosphorylation biological_process

SH2D1B Polyclonal Antibody

SH2D1B Antibody (11871-1-AP) in ICC/IF

产品信息

11871-1-AP

免疫印迹 (WB)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

流式细胞分析 (Flow)

免疫沉淀 (IP)

其他PubMed (Misc)

不适用 (N/A)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

产品详细信息

靶标信息

生物信息学

性能保障

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