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SHBG Antibody (MA5-26321) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded carcinoma of human liver tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a SHBG monoclonal antibody (Product # MA5-26321).
产品信息
MA5-26321
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI1D10
抗原
Full length human recombinant protein of SHBG produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2725346
靶标信息
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ABP; Androgen binding protein (ABP); SBP; Sex hormone-binding globulin; Sex hormone-binding globulin (SHBG); Sex steroid binding protein (SBP); Sex steroid-binding protein; SHBG; TeBG; Testis-specific androgen-binding protein; Testosterone binding beta globulin; testosterone-binding beta-globulin; Testosterone-estradiol-binding globulin; Testosterone-Estradiol-Binding Globulin (TEBG); Testosterone-estrogen-binding globulin
基因别名: ABP; SBP; SHBG; TEBG
UniProt ID: (Human) P04278
Entrez Gene ID: (Human) 6462
