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产品信息
12436-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SHC3 Fusion Protein Ag3115 (244-594 aa encoded by BC026314)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: IIANHHMRS ISFASGGDPD TTDYVAYVTK DPVNRRACHI LECCDGLAQD VIGSIGQAFE LRFKQYLQCP TKIPALHDRM QSLDEPWTEE EGDGSDHPYY NSIPSKMPPP GGFLDTRLKP RPHAPDTAQF AGKEQTYYQG RHLGDTFGED WQQTPLRQGS SDIYSTPEGK LHVAPTGEAP TYVNTQQIPP QAWPAAVSSA ESSPRKDLFD MKPFEDALKN QPLGPVLSKA ASVECISPVS PRAPDAKMLE ELQAETWYQG EMSRKEAEGL LEKDGDFLVR KSTTNPGSFV LTGMHNGQAK HLLLVDPEGT IQTKDRVFDS ISHLINHHLE SSLPIVSAGS ELCLQQPVER KQ (244-594 aa encoded by BC026314)
靶标信息
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: N-Shc; Neuronal Shc; Protein Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC-transforming protein 3; SHC-transforming protein C; Shc3 p51; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3
基因别名: N-Shc; NSHC; RAI; SHC3; SHCC
UniProt ID: (Human) Q92529, (Mouse) Q3ZAX2
Entrez Gene ID: (Human) 53358, (Rat) 114858, (Mouse) 20418
MAPK cascade
transmembrane receptor protein tyrosine kinase signaling pathway
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
central nervous system development
learning or memory
synaptic transmission, glutamatergic
positive regulation of GTPase activity
intracellular signal transduction
signal transduction
