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产品信息
PA5-58063
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2647288
产品详细信息
Immunogen sequence: VREVLVRALP VEELRVYCAL LAGKAAVLAQ QRNLDERIRL LQDQLDAIRD DLGHHAPSPS PARPPGTCPP VQPPFPLLLT
Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 51%.
靶标信息
SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.
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生物信息学
蛋白别名: Apical protein 2; Protein Shroom1; Shroom
基因别名: APXL2; KIAA1960; SHROOM1
UniProt ID: (Human) Q2M3G4
Entrez Gene ID: (Human) 134549
