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Positive Control: Expressed by peripheral blood leukocytes (eosinophils lung monocytes and a natural killer cell subpopulation). Isoform 5 is found in lymph node ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow spleen a
Cellular Location: Cell surface. Secreted.
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: sialic acid binding Ig-like lectin 10 Ig-like lectin 7; Sialic acid-binding Ig-like lectin 10; Siglec; Siglec-10; siglec-like gene 2; Siglec-like protein 2
基因别名: PRO940; SIGLEC-10; SIGLEC10; SLG2; UNQ477/PRO940
UniProt ID: (Human) Q96LC7
Entrez Gene ID: (Human) 89790