Product References
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
International immunopharmacology
Huang R,Cai L,Ma X,Shen K
Sat Apr 01 00:00:00 EDT 2023
Specific detection and deletion of the sigma-1 receptor widely expressed in neurons and glial cells in vivo.
Journal of neurochemistry
Liu Q,Guo Q,Fang LP,Yao H,Scheller A,Kirchhoff F,Huang W
Wed Mar 01 00:00:00 EST 2023
Specific detection and deletion of the sigma-1 receptor widely expressed in neurons and glial cells in vivo.
Journal of neurochemistry
Liu Q,Guo Q,Fang LP,Yao H,Scheller A,Kirchhoff F,Huang W
Wed Mar 01 00:00:00 EST 2023
Regenerative peripheral nerve interface prevents neuroma formation after peripheral nerve transection.
Neural regeneration research
Wang Z,Yi XZ,Yu AX
Sat Apr 01 00:00:00 EDT 2023
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Nature communications
Zhao Y,Hu D,Wang R,Sun X,Ropelewski P,Hubler Z,Lundberg K,Wang Q,Adams DJ,Xu R,Qi X
Wed Mar 02 00:00:00 EST 2022
Morphological, behavioral and cellular analyses revealed different phenotypes in Wolfram syndrome wfs1a and wfs1b zebrafish mutant lines.
Human molecular genetics
Crouzier L,Richard EM,Diez C,Alzaeem H,Denus M,Cubedo N,Delaunay T,Glendenning E,Baxendale S,Liévens JC,Whitfield TT,Maurice T,Delprat B
Tue Aug 23 00:00:00 EDT 2022
Sigma‑1 receptor overexpression promotes proliferation and ameliorates cell apoptosis in β‑cells.
Molecular medicine reports
Ke M,Lin F,Wang H,He G,Feng J,Song L,Xu Y,Liu J
Sun May 01 00:00:00 EDT 2022
Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.
Experimental neurology
Liu D,Yang L,Liu P,Ji X,Qi X,Wang Z,Chi T,Zou L
Sat Jan 01 00:00:00 EST 2022
Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.
Experimental neurology
Liu D,Yang L,Liu P,Ji X,Qi X,Wang Z,Chi T,Zou L
Sat Jan 01 00:00:00 EST 2022
Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.
Experimental neurology
Liu D,Yang L,Liu P,Ji X,Qi X,Wang Z,Chi T,Zou L
Sat Jan 01 00:00:00 EST 2022
Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.
Experimental neurology
Liu D,Yang L,Liu P,Ji X,Qi X,Wang Z,Chi T,Zou L
Sat Jan 01 00:00:00 EST 2022
A new insight on peripheral nerve repair: the technique of internal nerve splinting.
Journal of neurosurgery
Luo X,Li B,Zhang D,Chen H,Zhou X,Yao C,Raza MA,Wang L,Tang N,Zheng G,Yan H
Fri Feb 25 00:00:00 EST 2022
Nerve-End Capping Treatment with a Polyglycolic Acid Conduit for Rat Sciatic Neuroma: A Preliminary Report.
Journal of reconstructive microsurgery
Onode E,Uemura T,Hama S,Yokoi T,Okada M,Takamatsu K,Nakamura H
Tue Nov 01 00:00:00 EDT 2022
Allosteric Modulation of the Sigma-1 Receptor Elicits Antipsychotic-like Effects.
Schizophrenia bulletin
Chen J,Li G,Qin P,Chen J,Ye N,Waddington JL,Zhen X
Tue Mar 01 00:00:00 EST 2022
NCS1 overexpression restored mitochondrial activity and behavioral alterations in a zebrafish model of Wolfram syndrome.
Molecular therapy. Methods & clinical development
Crouzier L,Richard EM,Diez C,Denus M,Peyrel A,Alzaeem H,Cubedo N,Delaunay T,Maurice T,Delprat B
Thu Dec 08 00:00:00 EST 2022
Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1-NMDAR pathway.
Pharmaceutical biology
Zhang Y,Ye G,Chen Y,Sheng C,Wang J,Kong L,Yuan L,Lin C
Thu Dec 01 00:00:00 EST 2022
Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1-NMDAR pathway.
Pharmaceutical biology
Zhang Y,Ye G,Chen Y,Sheng C,Wang J,Kong L,Yuan L,Lin C
Thu Dec 01 00:00:00 EST 2022
Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1-NMDAR pathway.
Pharmaceutical biology
Zhang Y,Ye G,Chen Y,Sheng C,Wang J,Kong L,Yuan L,Lin C
Thu Dec 01 00:00:00 EST 2022
Serine palmitoyltransferase assembles at ER-mitochondria contact sites.
Life science alliance
Aaltonen MJ,Alecu I,König T,Bennett SA,Shoubridge EA
Tue Feb 01 00:00:00 EST 2022
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
Acta neuropathologica
Shang Y,Sun X,Chen X,Wang Q,Wang EJ,Miller E,Xu R,Pieper AA,Qi X
Tue Nov 01 00:00:00 EDT 2022
PACS2-TRPV1 axis is required for ER-mitochondrial tethering during ER stress and lung fibrosis.
Cellular and molecular life sciences : CMLS
Knoell J,Chillappagari S,Knudsen L,Korfei M,Dartsch R,Jonigk D,Kuehnel MP,Hoetzenecker K,Guenther A,Mahavadi P
Fri Feb 25 00:00:00 EST 2022
The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo.
Journal of cell science
Han S,Zhao F,Hsia J,Ma X,Liu Y,Torres S,Fujioka H,Zhu X
Thu Jul 01 00:00:00 EDT 2021
Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats.
Molecular neurobiology
Ooi K,Hu L,Feng Y,Han C,Ren X,Qian X,Huang H,Chen S,Shi Q,Lin H,Wang J,Zhu D,Wang R,Xia C
Wed Dec 01 00:00:00 EST 2021
Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats.
Molecular neurobiology
Ooi K,Hu L,Feng Y,Han C,Ren X,Qian X,Huang H,Chen S,Shi Q,Lin H,Wang J,Zhu D,Wang R,Xia C
Wed Dec 01 00:00:00 EST 2021
Sigma-1 Receptor Is Critical for Mitochondrial Activity and Unfolded Protein Response in Larval Zebrafish.
International journal of molecular sciences
Crouzier L,Denus M,Richard EM,Tavernier A,Diez C,Cubedo N,Maurice T,Delprat B
Wed Oct 13 00:00:00 EDT 2021
Sigma receptor knockdown augments dysfunction and apoptosis of beta cells induced by palmitate.
Experimental biology and medicine (Maywood, N.J.)
Ke M,He G,Wang H,Cheng S,Xu Y
Thu Jul 01 00:00:00 EDT 2021
Sulforaphane Balances Ca2+ Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Molecular nutrition & food research
Tian S,Lei P,Zhang J,Sun Y,Li B,Shan Y
Thu Jul 01 00:00:00 EDT 2021
Nerve capping treatment using a bioabsorbable nerve conduit with open or closed end for rat sciatic neuroma.
Clinical neurology and neurosurgery
Hama S,Uemura T,Onode E,Yokoi T,Okada M,Takamatsu K,Nakamura H
Fri Oct 01 00:00:00 EDT 2021
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Neuropharmacology
Wang M,Wan C,He T,Han C,Zhu K,Waddington JL,Zhen X
Wed Sep 15 00:00:00 EDT 2021
Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS.
The Journal of cell biology
Niu F,Liao K,Hu G,Sil S,Callen S,Guo ML,Yang L,Buch S
Mon Feb 04 00:00:00 EST 2019
Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS.
The Journal of cell biology
Niu F,Liao K,Hu G,Sil S,Callen S,Guo ML,Yang L,Buch S
Mon Feb 04 00:00:00 EST 2019
Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS.
The Journal of cell biology
Niu F,Liao K,Hu G,Sil S,Callen S,Guo ML,Yang L,Buch S
Mon Feb 04 00:00:00 EST 2019
Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS.
The Journal of cell biology
Niu F,Liao K,Hu G,Sil S,Callen S,Guo ML,Yang L,Buch S
Mon Feb 04 00:00:00 EST 2019
Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS.
The Journal of cell biology
Niu F,Liao K,Hu G,Sil S,Callen S,Guo ML,Yang L,Buch S
Mon Feb 04 00:00:00 EST 2019
DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1.
Proceedings of the National Academy of Sciences of the United States of America
Liu Y,Ma X,Fujioka H,Liu J,Chen S,Zhu X
Tue Dec 10 00:00:00 EST 2019
Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury.
Aging
Zhai M,Liu C,Li Y,Zhang P,Yu Z,Zhu H,Zhang L,Zhang Q,Wang J,Wang J
Mon Nov 04 00:00:00 EST 2019
Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.
Proteomics
Wang X,Wen Y,Dong J,Cao C,Yuan S
Sun Jul 01 00:00:00 EDT 2018
Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.
Proteomics
Wang X,Wen Y,Dong J,Cao C,Yuan S
Sun Jul 01 00:00:00 EDT 2018
Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.
Proteomics
Wang X,Wen Y,Dong J,Cao C,Yuan S
Sun Jul 01 00:00:00 EDT 2018
Protective effect of a novel sigma-1 receptor agonist is associated with reduced endoplasmic reticulum stress in stroke male mice.
Journal of neuroscience research
Morihara R,Yamashita T,Liu X,Nakano Y,Fukui Y,Sato K,Ohta Y,Hishikawa N,Shang J,Abe K
Mon Oct 01 00:00:00 EDT 2018
Protective effect of a novel sigma-1 receptor agonist is associated with reduced endoplasmic reticulum stress in stroke male mice.
Journal of neuroscience research
Morihara R,Yamashita T,Liu X,Nakano Y,Fukui Y,Sato K,Ohta Y,Hishikawa N,Shang J,Abe K
Mon Oct 01 00:00:00 EDT 2018
ALS-Associated Endoplasmic Reticulum Proteins in Denervated Skeletal Muscle: Implications for Motor Neuron Disease Pathology.
Brain pathology (Zurich, Switzerland)
Jesse CM,Bushuven E,Tripathi P,Chandrasekar A,Simon CM,Drepper C,Yamoah A,Dreser A,Katona I,Johann S,Beyer C,Wagner S,Grond M,Nikolin S,Anink J,Troost D,Sendtner M,Goswami A,Weis J
Wed Nov 01 00:00:00 EDT 2017
ALS-Associated Endoplasmic Reticulum Proteins in Denervated Skeletal Muscle: Implications for Motor Neuron Disease Pathology.
Brain pathology (Zurich, Switzerland)
Jesse CM,Bushuven E,Tripathi P,Chandrasekar A,Simon CM,Drepper C,Yamoah A,Dreser A,Katona I,Johann S,Beyer C,Wagner S,Grond M,Nikolin S,Anink J,Troost D,Sendtner M,Goswami A,Weis J
Wed Nov 01 00:00:00 EDT 2017
Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels.
CNS neuroscience & therapeutics
Li D,Zhang SZ,Yao YH,Xiang Y,Ma XY,Wei XL,Yan HT,Liu XY
Fri Dec 01 00:00:00 EST 2017
Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels.
CNS neuroscience & therapeutics
Li D,Zhang SZ,Yao YH,Xiang Y,Ma XY,Wei XL,Yan HT,Liu XY
Fri Dec 01 00:00:00 EST 2017
Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels.
CNS neuroscience & therapeutics
Li D,Zhang SZ,Yao YH,Xiang Y,Ma XY,Wei XL,Yan HT,Liu XY
Fri Dec 01 00:00:00 EST 2017
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhang X,Wu F,Jiao Y,Tang T,Yang L,Lu C,Zhang Y,Zhang Y,Bai Y,Chao J,Teng G,Yao H
Fri Sep 01 00:00:00 EDT 2017
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhang X,Wu F,Jiao Y,Tang T,Yang L,Lu C,Zhang Y,Zhang Y,Bai Y,Chao J,Teng G,Yao H
Fri Sep 01 00:00:00 EDT 2017
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhang X,Wu F,Jiao Y,Tang T,Yang L,Lu C,Zhang Y,Zhang Y,Bai Y,Chao J,Teng G,Yao H
Fri Sep 01 00:00:00 EDT 2017
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhang X,Wu F,Jiao Y,Tang T,Yang L,Lu C,Zhang Y,Zhang Y,Bai Y,Chao J,Teng G,Yao H
Fri Sep 01 00:00:00 EDT 2017
Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel.
Frontiers in pharmacology
Zhang K,Zhao Z,Lan L,Wei X,Wang L,Liu X,Yan H,Zheng J
Thu Oct 01 00:00:00 EDT 2020
Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel.
Frontiers in pharmacology
Zhang K,Zhao Z,Lan L,Wei X,Wang L,Liu X,Yan H,Zheng J
Thu Oct 01 00:00:00 EDT 2020
Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel.
Frontiers in pharmacology
Zhang K,Zhao Z,Lan L,Wei X,Wang L,Liu X,Yan H,Zheng J
Thu Oct 01 00:00:00 EDT 2020
Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel.
Frontiers in pharmacology
Zhang K,Zhao Z,Lan L,Wei X,Wang L,Liu X,Yan H,Zheng J
Thu Oct 01 00:00:00 EDT 2020
Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons.
Cell death & disease
Ka M,Kook YH,Liao K,Buch S,Kim WY
Thu Oct 13 00:00:00 EDT 2016
Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons.
Cell death & disease
Ka M,Kook YH,Liao K,Buch S,Kim WY
Thu Oct 13 00:00:00 EDT 2016
Hereditary spastic paraplegia-linked REEP1 modulates endoplasmic reticulum/mitochondria contacts.
Annals of neurology
Lim Y,Cho IT,Schoel LJ,Cho G,Golden JA
Sun Nov 01 00:00:00 EDT 2015
Hereditary spastic paraplegia-linked REEP1 modulates endoplasmic reticulum/mitochondria contacts.
Annals of neurology
Lim Y,Cho IT,Schoel LJ,Cho G,Golden JA
Sun Nov 01 00:00:00 EDT 2015