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SIN3B Antibody (PA5-30680) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SIN3B was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: SIN3B Polyclonal Antibody (Product # PA5-30680) diluted at 1:500. Red: phalloidin, a cytoskeleton marker. Scale bar = 10 µm.
产品信息
PA5-30680
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 115 and 355 of Human SIN3B
偶联物
形式
Liquid
浓度
0.96 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548154
产品详细信息
Recommended positive controls: HCT116.
Predicted reactivity: Mouse (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Histone deacetylase complex subunit Sin3b; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b
基因别名: KIAA0700; SIN3B
UniProt ID: (Human) O75182
Entrez Gene ID: (Human) 23309
