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Immunogen sequence: LISYYVKRQP AIQKEDQGTI HQLLHQFVPS LFFSQQLDLG ASEESADEDR DSPQGQTTDP SERKKPAPGP HSSPPEEKGA FGDAPATEQP P
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Histone deacetylase complex subunit Sin3b; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b
基因别名: KIAA0700; SIN3B
UniProt ID: (Human) O75182
Entrez Gene ID: (Human) 23309