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SIPA1L2 Antibody (BS-7927R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded human cervical cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-SIPA1L2 Polyclonal Antibody, Unconjugated (bs-7927R) at 1:500 overnight at 4°C, followed by a conjugated secondary... View More
产品信息
BS-7927R
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human SIPA1L2, amino acids 251-350.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: serine-rich synapse associated protein 2; Serine-rich synapse-associated protein; signal-induced proliferation-associated 1 like 2; Signal-induced proliferation-associated 1-like protein 2; SIPA1-like protein 2; SPA-1-like 2
基因别名: BC058408; Kiaa0545; KIAA1389; mKIAA1389; Sersap2; SIPA1L2; SPAL2; Spar2
UniProt ID: (Human) Q9P2F8, (Mouse) Q80TE4, (Rat) Q5JCS6
Entrez Gene ID: (Human) 57568, (Mouse) 244668, (Rat) 361442
