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SIRP gamma Antibody (PA5-47627) in WB
Western blot analysis of SIRP gamma in NK‚92 human natural killer lymphoma cell line, Jurkat human acute T cell leukemia cell line, and human thymus tissue. Samples were incubated in SIRP gamma polyclonal antibody (Product # PA5-47627) using a dilution of 0.5 µg/mL followed by a HRP-conjugated Anti-Sheep IgG secondary antibody. Specific bands were detected for SIRPγ/CD172g at approximately 45-50 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47627
产品规格
种属反应
Human
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHO-derived recombinant human SIRP gamma/CD172g Val64-Ser364, (Val263Ala) and (Ser286Leu)
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2576834
产品详细信息
In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) SIRP alpha, rhSIRP beta 1, and recombinant mouse SIRP alpha is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
靶标信息
SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal-regulatory protein beta 2; Signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRP-b2; SIRP-beta-2; SIRP-gamma
基因别名: bA77C3.1; CD172g; SIRP-B2; SIRPB2; SIRPG; SIRPgamma
UniProt ID: (Human) Q9P1W8
Entrez Gene ID: (Human) 55423
